STUDY OF ANTIBACTERIAL EFFECT OF SOME PLANT’S CANDIDATES ON GRAM-NEGATIVE BACTERIA

Abstract

The increase of the mortality after surgical operations is directly connected with opportunistic microorganisms. Long time rehabilitation and increasing demand for new generations of antibiotics is elevate the problem to new level. The pharmacological companies from around the world try to get solution to high level of resistance of opportunistic microorganisms. However, evolution in the genetic resistance of microorganisms is uncontrollable and the production of synthetic antibiotics is demanding a lot of struggle and cost billions of dollars. Nowadays, traditional medicine is familiar and popular among different countries. This work includes study on antimicrobial activity of extracts of endemic plants in Kazakhstan and several commercially available plants. The list of plants represented in the study are: Thuja occidentalis L., Amygdalus ledebouriana Schltdl., Ferula soongarica Pall. ex Spreng., Zingiber officinale Roscoe., Allium sativum L., Armoracia rusticana P.G. Gaertn., B. Mey. & Scherb., Apium graveolens L. Opportunistic microorganisms that was used during the study are: Escherichia coli and Pseudomonas aeruginosa. Thus, A. sativum revealed antibacterial effect against E. coli at concentration 25% which is the lowest concentration that was presented, while to the extracts of A. ledebouriana both of the strains were sensitive.